tumor microenvironment

High-quality sample preparation, single-cell analysis, and ultra-high content spatial proteomics for multi-dimensional research workflows.

Jennifer Munson shares how teamwork and collaboration have fostered her research at the intersection of creativity and clinical discovery.

Human and mouse oral tumors recruit nerves to produce peptides that the cancer cells need to survive—but this process can be blocked with a migraine drug.

Innovative strategies drive stem cell repair of organ damage.

Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests. 

Whether the finding of a novel mechanism for cancer-related pain can lead to better treatments for neuropathic pain in people remains to be seen.

Starving glioblastoma tumors of the cholesterol made by astrocytes could suppress brain cancer progression.

Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.

At Brigham and Women’s Hospital, the cancer biologist is combining research into the tumor microenvironment with the principles of neuroscience to tease apart how cancers grow—and how to stop them.

Single cell and spatial assays provide information on different aspects of cancer.

Shannon Oda will discuss how to develop novel engineered fusion proteins to improve T cell therapies against hematological and solid tumors.

Cancer immunotherapy targets the tumor microenvironment, blocking the molecular pathways that tumors exploit to prevent immune cell activity.

Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.

Changes to protein glycosylation play a major role in dictating cancer progression and prognosis, but could they also present biomarkers or therapeutic targets?

A growing appreciation of the bacterial assemblages that live within tumors has researchers striving to understand and capitalize on their role.

From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.

The immune cells facilitate healing, but they may also help tumors metastasize to the lungs after injury, a study in mice finds.

Dario Vignali and Peter Westcott will explore the importance of understanding immune-cancer mechanistic interactions for developing therapeutic approaches.

Liquid biopsies: A new era in blood-based cancer detection methods

Single cell and spatial analyses help solve the mysteries of cancer.