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3D cartoon of a blue and green prokaryote on a teal background. Part of the cell is cutaway to reveal its circular chromosome.
A Hunt for Clues to the Origins of the Eukaryotic Immune System
Homologous defense proteins in archaea and eukaryotes point to these early prokaryotes' role in the immune system of modern complex organisms.
A Hunt for Clues to the Origins of the Eukaryotic Immune System
A Hunt for Clues to the Origins of the Eukaryotic Immune System

Homologous defense proteins in archaea and eukaryotes point to these early prokaryotes' role in the immune system of modern complex organisms.

Homologous defense proteins in archaea and eukaryotes point to these early prokaryotes' role in the immune system of modern complex organisms.

Microbiology

Image of concentric circles cut into a grass lawn.
Bacteria’s Stress Strategy: Slow Down to Avoid the Crowd
Laura Tran, PhD | Dec 2, 2024 | 4 min read
Computer simulations highlight how bacteria slow their growth to avoid overcrowding, a behavior that may inform pathogen control. 
A photo of a 96-well microplate showcasing serial dilutions of purple dye solution.
Achieving Consistency in Serial Dilutions
The Scientist Staff | Dec 2, 2024 | 2 min read
Researchers ensure the success of their serial dilution-based assays by using optimized protocols and advanced liquid handling tools.
A young child holding her bruised knee.
A Beneficial Bacterium Helps Wounds Heal
Sneha Khedkar | Dec 2, 2024 | 5 min read
A bacterium found in the wound microbiome can accelerate healing, highlighting the potential for microbiota-based wound therapies.
Image of a showerhead with running water. There is a soap dispenser and toothbrush on a wire shelf in the shower.
A Viral Investigation of Bathroom Biomes
Laura Tran, PhD | Nov 26, 2024 | 4 min read
Hidden on toothbrushes and showerheads, bacteriophages reveal a viral ecosystem and its potential to create healthier living spaces.
A cartoon of pills and bacteria along the human intestine.
An Antibiotic That Distinguishes Friend from Foe
Sneha Khedkar | Nov 19, 2024 | 4 min read
A novel compound targets an essential transport system found only in disease-causing bacteria, leaving commensal bacteria unharmed. 
A researcher holds a Petri dish containing many bacterial colonies in red colored culture medium.
Exploring the Landscape of Bacterial Culture Media
Priyom Bose, PhD | Nov 15, 2024 | 10 min read
Culture media contain various components that promote and support bacterial growth and differentiation.
A person works with their sourdough starter in the kitchen.
Bakers Rise Up to Tackle Sourdough Mysteries
Laura Tran, PhD | Nov 15, 2024 | 2 min read
Donated sourdough starters helped researchers uncover the factors that influence microbial communities in these living cultures.
Close up of ultraviolet light box during the preparation of an agarose electrophoresis gel used in DNA separation.
Automate and Illuminate Bioimaging Assays
The Scientist Staff | Nov 15, 2024 | 2 min read
Intuitive and automated chemiluminescence detection empowers scientists with accessible image acquisition and analyses.
Modern open plan office with white desks, computers, and chairs in the foreground and a vertical plant wall in the background.
Rewilding Urban Spaces Boosts Immune Health
Danielle Gerhard, PhD | Nov 15, 2024 | 2 min read
From daycares to indoor gardens, scientists are bringing nature back into cities to improve immune regulation.
A herd of elephants is walking in a river in a forest.
Elephant Deaths Trigger a Kodo-Millet Fungus Investigation in India
Sneha Khedkar | Nov 14, 2024 | 4 min read
When multiple elephants were found dead in a national park in India, microbiologists turned to investigate their prime suspect: fungi. 
A doctor holds a model of the female reproductive system.
Modeling the Human Cervix on a USB-Sized Chip
Sneha Khedkar | Nov 13, 2024 | 4 min read
Microfluidic chips that mimic the complex human cervical environment provide a platform to study the reproductive tract and associated infections like bacterial vaginosis.
Photo of a brown soy pulp patty sitting in a cream sauce alongside a cucumber and tomato salad and baked yams.
How Can Fungi Address the Global Food Waste Problem?
Danielle Gerhard, PhD | Nov 12, 2024 | 8 min read
Scientists are reimagining the food system, turning to fungal fermentation as a sustainable method for transforming food byproducts into tasty treats.
3D illustration of white Candida albicans yeast cells growing against host tissue.
A Fungal Messenger Impairs Immune Cell Function
Shelby Bradford, PhD | Nov 8, 2024 | 3 min read
Farnesol, a fungal signaling molecule, alters lipid synthesis in dendritic cells, causing mitochondrial dysfunction and decreased inflammatory responding.
3D illustration of dark, oval parasites invading translucent host cells with blue nuclei.
Live Imaging Intracellular Parasites Reveals Changes to Host Metabolism
Shelby Bradford, PhD | Nov 6, 2024 | 4 min read
Researchers found that Toxoplasma gondii increased the host cell’s metabolic activity, offering insights into potential treatment strategies.
Bluish-grey circles of fuzzy mold grow in a Petri dish.
How a Moldy Cantaloupe Took Fleming’s Penicillin from Discovery to Mass Production
Hannah Thomasy, PhD | Nov 4, 2024 | 10+ min read
Alexander Fleming’s 1928 discovery of a mold with antibacterial properties was only the first serendipitous event on the long road to penicillin as a life-saving drug.
<em >Wolbachia</em> bacteria, marked in green, are found in a wasp&rsquo;s egg, where the wasp&rsquo;s DNA is shown in blue.
A Microbial Ally to Bring Science to the Masses
Mariella Bodemeier Loayza Careaga, PhD | Nov 1, 2024 | 2 min read
By identifying Wolbachia in arthropods, science-enthusiast citizens can help researchers sample the bacteria’s hosts.
A close up photo showing wells in a 96-well plate.
How to Optimize OD600 Measurements
The Scientist Staff | Nov 1, 2024 | 2 min read
Optical density can be affected by sample conditions, the state of the measuring vessel, and instrument configuration.
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Transforming 3D biology using AI: Tomocube’s HT-X1™ Plus accelerates cellular and organoids label-free analysis
Tomocube | Oct 31, 2024 | 2 min read
This new system raises the bar in high-resolution, high-throughput 3D imaging for cells and organoids, providing researchers with faster, more detailed, and more accurate insights into biological processes.
A reddish brown ant with a whitish fungal stalk growing out of it.
Zombie Fungi Hijack Hosts’ Brains
Hannah Thomasy, PhD | Oct 29, 2024 | 10+ min read
Mind-controlling fungi are changing the ways that scientists understand host-parasite relationships.
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