protein

Environmental pressure seems to spawn changes in the intrinsically disordered regions of enzymes in polar yeasts, allowing them to adapt to extreme cold.

Researchers optimize chromatography-based workflows to purify biomolecules at scale.

Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.

The new fossil from Laos helps answer the question of how some people from Oceania carry DNA from the ancient hominin.

Known as SLiMs, these stretches of up to 10 amino acids play notable roles in cell biology, including responses to viral invasion.

Only recently appreciated as critical components of cellular functions, unstructured stretches of amino acids called SLiMs are key to viral-host interactions.

Researchers engineered strands of RNA that can link amino acids together, suggesting a way that RNA and proteins may have emerged together to create the earliest forms of life.

Miriam Merad and Harrison Specht will discuss how single cell proteomics complement other omics methods to provide insight into disease pathophysiology and treatment.

Changes to protein glycosylation play a major role in dictating cancer progression and prognosis, but could they also present biomarkers or therapeutic targets?

Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.

Adapting DNA nanopore sequencing to peptides allows researchers to identify single amino acid differences.

By breaking down urea, the animals’ gut bacteria recycle nitrogen, which can be then used to build new molecules during prolonged fasting.

An RNA-modifying enzyme passed to daughter cells during budding allows yeast cells to switch between faster- and slower-growing phenotypes.

Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease.

A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.

Researchers provide evidence that the Alzheimer’s-associated protein calibrates a signaling pathway that is conserved across the animal kingdom.

The University of California, Santa Barbara, cell biologist is investigating the formation and functions of the peroxisome, an organelle which exists in many copies in each cell and can be created, lost, or altered to meet the cell’s metabolic needs.

His career bridged impactful research in molecular biology and biochemistry with prolific science writing for academic and nonacademic audiences alike.

A modified protein expression system that does not require bacterial transformation

A technique that reversibly bundles tagged cargo into artificial membraneless compartments gives scientists the ability to switch cell processes on and off.