What’s the Difference Between a Voltage Clamp and a Current Clamp?
What’s the Difference Between a Voltage Clamp and a Current Clamp?
Depending on the “clamped” parameter, patch clamp configurations probe different aspects of a cell's electrical activity.
Depending on the “clamped” parameter, patch clamp configurations probe different aspects of a cell's electrical activity.
Patch clamping
Eavesdropping on Ion Channels Using the Patch Clamp Technique
Laura Tran, PhD | Sep 13, 2024 | 10+ min read
Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed.
Famed Neuroscientist Charles Stevens Dies at 88
Lisa Winter | Nov 9, 2022 | 3 min read
His work blended biology and the methods of theoretical physics to explain neural networks.
Top Technical Advances in 2017
Shawna Williams | Dec 24, 2017 | 3 min read
The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.
Robotic Patch Clamping Gains Eyes
Diana Kwon | Aug 30, 2017 | 4 min read
Two groups of scientists combined automation with two-photon microscopy to target and record specific neurons in living animals.
New and Old Techniques in Modern Neuroscience
Alison F. Takemura | Oct 1, 2016 | 6 min read
Imaging and manipulating the brain has come a long way from electrodes and the patch clamp, though such traditional tools remain essential.
Cutting the Wire
Jeffrey M. Perkel | Dec 1, 2014 | 8 min read
Optical techniques for monitoring action potentials