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A small blue cell undergoing cell death next to a larger amber cell with extensive projections.
Older Oligodendrocytes Live Longer Despite Damage
Tracking oligodendrocytes across their lifespans could help scientists better understand neuronal aging and degenerative diseases. 
Older Oligodendrocytes Live Longer Despite Damage
Older Oligodendrocytes Live Longer Despite Damage

Tracking oligodendrocytes across their lifespans could help scientists better understand neuronal aging and degenerative diseases. 

Tracking oligodendrocytes across their lifespans could help scientists better understand neuronal aging and degenerative diseases. 

Neuroscience

Six tubes, each with black dots representing flies, each fly encircled in blue, green, or red.
Combating Age-Related Motor Decline
Aparna Nathan, PhD | Aug 23, 2024 | 4 min read
Increasing levels of the protein Trio preserved synaptic function and motor abilities in aging flies.
Exploring the Many Facets of Single Cell Methylation
Exploring the Many Facets of Single Cell Methylation
The Scientist Staff | Aug 20, 2024 | 1 min read
In this webinar, Austin Holmes and Jason Koth will discuss how to overcome single cell methylation and data analysis hurdles.
A circular pattern of red, blue, and yellow bolts of electricity on a black background.
Current Events: Bioelectrical Gradients Guide Stem Cell Morphology
Iris Kulbatski, PhD | Aug 16, 2024 | 3 min read
Electrically conductive hydrogels may hold the power to advance the use of stem cells for neural engineering. 
An illustration of lungs being infected by microbes.
Bacteria Put on an Invisibility Cloak to Cause Asymptomatic Infections 
Sahana Sitaraman, PhD | Aug 15, 2024 | 5 min read
Biofilms prevent Pseudomonas aeruginosa toxins from being detected by sensory neurons, tricking the body into not looking sick.
The image shows a rendering of a human brain viewed from a lateral perspective with the cerebellum, highlighted in yellow and orange, is situated at the bottom part of the brain where the cerebrum connects with the brainstem. 
Revealing the Mutation Behind a Rare Neurological Disease
Claudia Lopez-Lloreda, PhD | Aug 2, 2024 | 3 min read
After 20 years, scientists studying patients with cerebellar degeneration discovered a mutation that disrupts autophagy.
Neurons in culture
Lighting Up the Neuronal Cytoskeleton
Mariella Bodemeier Loayza Careaga, PhD | Aug 1, 2024 | 2 min read
By combining microscopy techniques with genome engineering, scientists revealed the complexities of the presynaptic actin cytoskeleton.
A drawing of a dopamine molecule with happy faces.
Debunking the Dopamine Detox Trend  
Hannah Thomasy, PhD | Jul 31, 2024 | 9 min read
The fad of temporarily fasting from pleasurable activities likely won’t “reset” dopamine levels and doesn’t accurately reflect this molecule’s nuanced functions.
A robot hand makes contact with a human finger on a dark blue background.
Fine Tuning Muscle Control with Light
Claudia Lopez-Lloreda, PhD | Jul 31, 2024 | 3 min read
By leveraging optogenetic stimulation for more precise muscle activation, scientists hope to advance neuroprosthetic technology.
Fluorescence microscopy image of the brain and nasal cavity roof, with blood vessels, microglia, and nuclei labeled.
Studying the Brain During Fungal Infections just got a Whole Lot Clearer
Shelby Bradford, PhD | Jul 30, 2024 | 4 min read
Researchers adapted microscopy techniques to identify rare instances of Cryptococcus neoformans in mice brains and lungs.
A photo of a newborn baby’s feet with a hospital bracelet.
Tiny Biomarkers for Small Patients with Brain Injuries
Charlene Lancaster, PhD | Jul 24, 2024 | 5 min read
Scientists identify potential microRNA-based diagnostic and predictive biomarkers of neonatal encephalopathy.
Conceptual illustration of a happy gut with colorful flowers on a blue background.
Researchers Use Groovy Science to Understand Gut Feelings
Iris Kulbatski, PhD | Jul 17, 2024 | 4 min read
A new microfluidics cell culture model recapitulates the basic biology of gut touch.
An illustration of brains on a pink background.
Advancing Neuroscience Research with CyTOF Technology
Standard BioTools | Jul 16, 2024 | 1 min read
Discover how researchers expand their understanding of neurological disorders by using cytometry by time of flight (CyTOF) analysis. 
Circular probes surrounding a cartoon of a human brain.
An Epigenetic Brain Scan
Aparna Nathan, PhD | Jul 16, 2024 | 4 min read
A lower-resolution spatial epigenomics method offers a cost-effective alternative to traditional single-cell approaches.
Rendering of a 3D printer working on bioprinting human brain tissue.
Crafting Mindscapes of the Brain
Laura Tran, PhD | Jul 15, 2024 | 2 min read
Functional human neural tissues assembled using 3D printing technology may provide insights into neural wiring.
MRI scan of a human head in profile
Gut Microbe Metabolites Lower Levels of Toxic Tau
Kamal Nahas, PhD | Jul 9, 2024 | 5 min read
Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.
Conceptual 3D illustration of DNA with multicolored base pairs on a black background.
Understanding Cell Type Specific 3D Genome Structure and DNA Methylation
Velsera | Jul 8, 2024 | 1 min read
A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types.
Illustration of a human brain shaped puzzle on a pink background. An electroencephalogram recording is depicted on top of the brain. 
How the Brain Selects What Experiences to Keep
Mariella Bodemeier Loayza Careaga, PhD | Jul 3, 2024 | 4 min read
A brain rhythm in the hippocampus tags events for replaying during sleep, revealing a potential mechanism for selecting experiences for long-term storage. 
A woman feels discomfort while she is thirsty (left), but she feels refreshed and rejuvenated when she has her first sip of water (right).
Why Does Drinking Water Feel so Rewarding When One is Parched?
Laura Tran, PhD | Jul 1, 2024 | 2 min read
With a thirst for knowledge, scientists delve into gut-brain pathways to understand liquid rewards.
Cluster of red, green, and yellow neurons
The Making of a Memory
Danielle Gerhard, PhD | Jul 1, 2024 | 2 min read
Sheena Josselyn discussed how she uses optogenetic tools to bias, express, and erase memories in mice.
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