metabolism

Cellular oxygen consumption in the brain may shed new light on Alzheimer’s disease onset, progression, and treatment.

When it comes to supplying their purine needs, cancer cells may use salvaged metabolites, according to a study in mice. 

While studying the metabolism of the developing chick embryo, Marià Alemany Lamana’s team acted quickly to avert an error.

Gene mutations in rotund retrievers shed light on the neural regulation of body weight.

An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds. 

Trypanosoma brucei infection induces fat breakdown, but this strategy benefits the host. 

Astronomically high blood sugar is no problem for these tiny speed demons.

As the closest reflection of biological phenotype, metabolomics provides critical information about human health and disease.

Spatial methods reveal immune cell formations in fat during early obesity.

A cell’s metabolic program provides insight into its fitness and function.

Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.

Exercise drives the liver to produce the CES2 enzyme, which circulates in blood and delivers some of the benefits of exercise in mice. 

Yeast cells share metabolites through extracellular space to extend the lifespan of the entire community.

A new era of reliable recombinant proteins makes it possible for researchers to replace tissue-derived biomarkers in a variety of diagnostic assays.

Microbiomes transplanted from women with anorexia nervosa into mice enhanced symptoms of the eating disorder, such as rapid weight loss and reduced appetite.

The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.

Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.

The presence of beneficial or detrimental microbes pulls the host toward health or disease.