insulin

The original work found that an anti-malaria drug or the neurotransmitter GABA could increase the number of insulin-producing pancreatic cells in mice.

Scientists engineered human cells to produce a molecule that stimulates insulin secretion in the presence of caffeine.

One patient with diabetes was able to reduce his medication use while receiving targeted electrical pulses.

A study of more than 450,000 people finds a certain genetic variant associated with eating more carbs is linked to a thicker waist and higher blood pressure, but less fat.  

The new classification system could help improve personalized medicine approaches to the disease.

Pancreatic cells engineered to produce insulin did not immediately provoke an immune response.

A small clinical trial demonstrates that peptide immunotherapy can halt the progression of early-stage type 1 diabetes.

A small patch of engineered cells makes an enzyme that stimulates insulin release.

Scientists have constructed three-dimensional maps depicting the size and location of insulin-producing islet cells in the mouse pancreas.

Researchers produce functional organs composed of both mouse and rat cells.

Insulin resistance and high levels of insulin and lipids all precede the development of metabolic dysfunction. Which metabolic factor is to blame?

Lipids and insulin play important roles in blood sugar regulation, and altered levels of either could kick start metabolic dysfunction.

Changes in diet can cause gut microbes to produce acetate, which in turn stimulates insulin secretion and obesity in rodents, scientists show.

Patients with neonatal progeroid syndrome lack a glucose-releasing hormone, while people with insulin resistance have an abundance.

Scientists grow gastric organs in vitro that can restore insulin production when transplanted into mice.

Researchers reprogram human skin cells to make insulin-producing pancreatic cells that can prevent diabetes in mice.

Guenther Boden, who linked insulin resistance with fatty acids in the blood, has passed away at age 80.

Overeating and inactivity lead to insulin resistance in just days—and oxidative stress is to blame.

Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.