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An illustration of a single cancer cell (in seafoam green) with four white blood cells (in green) attached to it.
The Circadian Clock Tells the Right Time for Immunotherapy
Administering immunotherapy when the tumor microenvironment is most susceptible to T cells enhances treatment efficacy in mice.
The Circadian Clock Tells the Right Time for Immunotherapy
The Circadian Clock Tells the Right Time for Immunotherapy

Administering immunotherapy when the tumor microenvironment is most susceptible to T cells enhances treatment efficacy in mice.

Administering immunotherapy when the tumor microenvironment is most susceptible to T cells enhances treatment efficacy in mice.

Immunology

Image of Lasker laureate Zhijian “James” Chen. He wears glasses and a light blue shirt under a dark blue sweater. He smiles at the camera.
DNA-Sensing Enzyme Wins the 2024 Lasker Award
Laura Tran, PhD | Sep 19, 2024 | 7 min read
Zhijian “James” Chen received this year’s Albert Lasker Award for discovering cGAS, an enzyme which scopes out DNA-based threats and alerts the immune system.
Two hands holding tweezers and dissecting single points in a DNA sequence.
From CRISPR to Prime Editing: The Evolution of the Genome Editing Revolution
Danielle Gerhard, PhD | Sep 17, 2024 | 5 min read
Even as CRISPR-based tools become a lab staple, scientists strive to tackle the associated technological challenges to improve their efficacy and safety.   
3D illustration of a cell with a teal nucleus.
In Search of FACS: The History of Fluorescence Activated Cell Sorting
Shelby Bradford, PhD | Sep 13, 2024 | 10+ min read
In the middle of the 20th century, science disciplines collided and set the stage for a technology that changed cell research.
Discover How Immunoassays Deliver Protein Biomarker Research Solutions
Protein Biomarker Research Solutions
The Scientist Creative Services Team in collaboration with MilliporeSigma | Sep 9, 2024 | 1 min read
Immunoassays help researchers across a range of applications from screening to targeted analysis.
A wound that is covered with a band-aid.
Why Pain During Wound Healing May be a Good Sign
Sneha Khedkar | Sep 5, 2024 | 4 min read
Sensory neurons grow into injured tissues and modulate the immune system to promote healing.
A syringe inserted into a vial of vaccine.
Engineered Yeast Brew a Vaccine Adjuvant 
Sahana Sitaraman, PhD | Sep 3, 2024 | 3 min read
Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.
Cartoon of a young girl sitting at a table looking at a collection of cartoon viruses.
Crafting Science Stories for Young Audiences
Danielle Gerhard, PhD | Sep 2, 2024 | 7 min read
Finding a narrative that resonates with the audience and serving it in their preferred format helps make science engaging, relatable, and fun.
Improving T Cell Tumor-Specificity Using Single Cell Co-culture
Improving T Cell Tumor-Specificity Using Single Cell Co-culture
The Scientist Staff | Aug 28, 2024 | 1 min read
In this webinar, Edward Han, Jospeh Zenga, and Tyce Kearl will discuss how optofluidic technologies unlock key immuno-oncology insights for translational applications.
On the left is a brain in blue connect by blue electricity-like lines to a heart in red on the right side of the image.
Can the Brain Help Heal a Broken Heart?
Hannah Thomasy, PhD | Aug 28, 2024 | 6 min read
Stimulation of neural reward pathways may help mice recover from heart attacks.
An illustration of a B cell secreting autoantibodies.
Autoimmune Diseases: An Alternative Application for Immunotherapy
The Scientist | Aug 23, 2024 | 1 min read
Learn how immunotherapy is revolutionizing autoimmune disorder treatment.
3D rendering of a transparent human torso to show the lungs and bronchiole structures in them.
Prenatal Inflammation Makes Mice Susceptible to Asthma
Shelby Bradford, PhD | Aug 20, 2024 | 4 min read
Maternal immune responses during mice gestation led to a hyperactive population of innate-like immune cells in offspring that contributed to altered lung composition and function.
A woman and a child sitting on a couch blowing their noses. 
A Better Mucus Model
Aparna Nathan, PhD | Aug 20, 2024 | 4 min read
A more realistic model of the mucus layer that lines the lungs and gut could provide important insights into the function of this critical defensive barrier.
Image shows the mosquito Aedes aegypti on top of human skin.
A Mosquito Protein Facilitates Zika Infection
Claudia Lopez-Lloreda, PhD | Aug 14, 2024 | 3 min read
A salivary protein in mosquitos can suppress host immune activity and aid viral transmission.
Discover How Scientists Use Spectral Flow Cytometry to Design Larger and More Flexible Panels
Unmixing the Fundamentals of Spectral Flow Cytometry
BD Biosciences | Aug 7, 2024 | 1 min read
Spectral flow cytometry collects the full emission spectrum of a fluorochrome, enabling multicolor panels with more parameters than conventional flow cytometry.
Electron microscopy image of Marburg virus false-colored red. 
Viral Research Gets Batty to Study Spillovers
Shelby Bradford, PhD | Aug 5, 2024 | 3 min read
Marburg virus enters humans from bats to cause viral hemorrhagic fever, but how it alters immune cells is unclear.
Two ferrets look out of a rectangular hole in a wooden structure.
Obesity Alters the Course of Influenza Infections
Hannah Thomasy, PhD | Aug 1, 2024 | 2 min read
Researchers explored the effects of obesity on the lung microenvironment in ferrets, searching for new therapeutic targets to protect vulnerable populations.
A blue T cell attacks a blue cancer cell
Characterizing Cancer via the Immune Response
The Scientist | Jul 30, 2024 | 1 min read
Researchers explore the immune system to further understand cancer and illuminate therapy development.
A smiling woman holds a young child outside in the park.
A Stranger to Oneself: The Mystery of Fetal Microchimerism
Hannah Thomasy, PhD | Jul 22, 2024 | 10 min read
During pregnancy, fetal cells invade maternal tissues and can persist for decades, but the effects of these non-self cells remain largely obscure.
Cross sections of a mouse colon, where RNAs are colored depending on the local expression profile.  
A Cellular Atlas of Gut Inflammation
Alejandra Manjarrez, PhD | Jul 19, 2024 | 4 min read
Researchers mapped tissue remodeling during colitis development in mice to explore how diverse cell types contribute and respond to the disease.  
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