hematopoietic stem cells

By coupling cell lineage tracking with molecular gene expression patterns, researchers deciphered how gene activity influences immune cell production.

Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.

New technologies and archival tissue biopsy samples enable exploration of changes in the bone marrow as people age.

The immune system's recovery from chronic alcohol use could take longer than some rehabilitation periods due to alcohol's effects on stem cells.

Editing epitopes expressed on the surfaces of transplanted hematopoietic stem cells renders them resistant to AML treatments without affecting their critical functions.

Next generation sequencing (NGS) core facility scientists and researchers discuss their latest work exploring novel cancer models and stem cells in space.

Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. 

Next-generation sequencing (NGS) core facility scientists and researchers new to NGS discuss their fruitful collaborations, highlighting how to receive expert help from genomics facilities.

Hematopietic stem cells (HSCs) are multipotent cells found in the blood and bone marrow with the ability to self-renew and differentiate into multiple cell types during bone marrow hematopoiesis

Chromosomal rearrangements reposition influential and often overlooked non-coding elements in the genome to hijack genes and cause cancer.

Scientists uncover the promise of mesenchymal stem cells (MSCs), also known as medicinal signaling cells, to modulate the immune system and regenerate tissue.

Margaret Nakamoto will introduce the BD Rhapsody™ Single-Cell Analysis System, and Ravi Majeti will discuss how he and his team used concurrent RNA and BD® AbSeq Antibody-oligo multiplexed surface marker analysis to improve HSPC clustering and characterize specific phenotypic states along unique hematopoietic differentiation trajectories.

A Chicago-based center that has long operated a clinical trial program for stem cell therapies, has stopped recruiting further patients as its chief, Richard Burt, leaves for a research sabbatical.

An experiment tests whether a protein treatment can help hematopoietic stem cells recover after mice are exposed to radiation.

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.

The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.

High levels of vitamin C absorbed by blood-forming stem cells are important for their normal development. 

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

Researchers identify transcription factors and environmental conditions necessary to reprogram human and mouse cells into cells that function like hematopoietic stem cells.