Genetics

A new database with more than 2,500 food metagenomes gives scientists a glimpse into the microbial diversity of the human diet.

Examining the advantages of saliva samples for genomics and microbiome researchers as a source of total nucleic acids. 

Standardized and scalable in vitro transcription reagents allow researchers to enhance and accelerate cell-free mRNA synthesis.

Citizen scientists help monitor monkey immune cells, providing a foundation for future work on stress, sociality, and aging.

A novel sequencing-based method revealed chromosome-specific telomere lengths, challenging prior models.

Humanity’s microscopic foes may be to blame for the ABO polymorphism.

The 2.4-million-year-old environmental DNA fragments collected from permafrost in northern Greenland unlock insights into an ancient ecosystem.

Enhancing protein diversity and guiding cellular functions, alternative splicing is a key dimension of genetic regulation.

A new study shows that a constellation of genetic changes link the timing of puberty to weight gain and other biological processes.

Python heart muscles ramp up their force to sustain metabolic activity to maintain increased metabolism during feeding.

CASGEVY^® is the first cell therapy based on the CRISPR/Cas9 technology, discoverers of which were awarded the Nobel Prize in Chemistry in 2020.

Liquid chromatography-mass spectrometry allows scientists to accurately assess the quantity and quality of synthesized oligonucleotides. 

Discover how scientists produce CRISPR-edited cell populations.

A new study employs a multiomic approach to study how cytomegalovirus activation impacts breast milk bioactive factors and the infant microbiota.

Sequencing advances deliver comprehensive insights into how genomic variation drives cancer initiation and progression.

Even as CRISPR-based tools become a lab staple, scientists strive to tackle the associated technological challenges to improve their efficacy and safety.   

Murine T cells that survived at least four host lifetimes offer insights into immunological senescence. 

For years, neuroscience research overlooked female subjects, creating a significant bias. Today, researchers actively rebalance the scales with more inclusive and diverse studies.

By postnatally providing a transcription factor important for brain development, researchers fixed abnormalities generated in utero in mice.