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Newborn heel prick test for genetic screening
Transforming Molecular Workflows for Newborn Screening
New PCR-based approaches simplify molecular testing for health issues in infants, making diagnostic approaches more accessible across laboratories.
Transforming Molecular Workflows for Newborn Screening
Transforming Molecular Workflows for Newborn Screening

New PCR-based approaches simplify molecular testing for health issues in infants, making diagnostic approaches more accessible across laboratories.

New PCR-based approaches simplify molecular testing for health issues in infants, making diagnostic approaches more accessible across laboratories.

Genetics

Illustration of a pink brain in a silhouette on a background with brainwaves. 
Sleep Disruptions and Impaired Muscle Control in Ataxia May Share a Culprit
Shelby Bradford, PhD | Nov 5, 2024 | 4 min read
Dysfunctional neurons in the cerebellum, a brain region that controls motor functions, reduced REM sleep in mice.
Fluorescent multicolored waveform lines on a black background.
Next-Generation PCR Instruments Boost Workflows 
The Scientist Staff | Nov 1, 2024 | 2 min read
Modern, intuitive, and reliable thermal cyclers excel at optimizing sequencing, cloning, and genotyping throughput.
A photo of blood vials arranged in rows.
Automating Liquid Biopsy: Unleashing New Potential in Diagnostics
Tecan | Oct 30, 2024 | 1 min read
Discover how automation increases the efficiency and reliability of blood-based liquid biopsy assays.
An artistic interpretation of CRISPR genome editing showing the cutting and changing of DNA segments.
A Small Genome Editing Nuclease Packs a Big Punch
Sahana Sitaraman, PhD | Oct 30, 2024 | 4 min read
For the past decade, scientists have relied almost exclusively on CRISPR-Cas systems for genome editing. Now, a smaller but equally efficient nuclease is here to compete. 
A team of scientists engaged in protein engineering experiments in a laboratory, showcasing advanced research techniques.
Insights Into Protein Engineering: Methods and Applications
Priyom Bose, PhD | Oct 29, 2024 | 7 min read
Synthetic biologists modify naturally occurring amino acid sequences to engineer proteins and enzymes for specific applications.
Image of blood in a test tube with the four base pairs of DNA in the background.
A Novel Polymerase Reduces Stutter in Forensic DNA Analysis
Laura Tran, PhD | Oct 28, 2024 | 4 min read
A breakthrough enzyme aims to resolve a persistent DNA artifact that has challenged forensic analysis for decades.
The two sections show an oval-shaped structure, some of which is red in color. The red-colored structure is larger in the image above.
Fathers’ Gut Bacteria Impact Offspring Health
Sneha Khedkar | Oct 25, 2024 | 4 min read
Gut microbiome disruption in male mice increases disease risk in offspring, indicating that preconception paternal health status can affect the next generation.
Illustration of a small microRNA in blue with additional microRNAs in the background. 
From Worm Anomaly to Nobel Prize: microRNAs Show Macro Impact
Danielle Gerhard, PhD | Oct 21, 2024 | 5 min read
Discovered 30 years ago, microRNAs are increasingly recognized as important regulators of cell physiology and human disease.
Cartoon humans standing on a DNA profile.
A Geneticist's Journey From a Lupus Victory to a Murder Case Verdict
Danielle Gerhard, PhD | Oct 21, 2024 | 10+ min read
Carola Vinuesa’s research has illuminated the genetics of lupus and helped to exonerate a mother falsely accused of murdering her four children. 
Test tubes containing urine samples
Achieving Better Test Sensitivity for Cancer Liquid Biopsies
DNA Genotek Inc. | Oct 18, 2024 | 1 min read
First-void urine has emerged as a promising sample type for cancer diagnostic test development.
Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids
Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids
The Scientist Staff | Oct 16, 2024 | 1 min read
In this webinar, Cole Cheng and Connie Rich will discuss the advantages of novel miniaturized plasmids for streamlining preclinical and clinical gene therapy development.
An African killifish 
How Cells Know Where to Grow After Injury
Deanna MacNeil, PhD | Oct 16, 2024 | 3 min read
Fish fins and single-cell sequencing help scientists glean new insights into tissue regeneration.
An illustration of the bacterial pathogen&nbsp;<em data-renderer-mark="true" >Streptococcus pyogenes</em>.
Genomic Pathogen Surveillance with Nanopore Sequencing
Oxford Nanopore Technologies | Oct 15, 2024 | 1 min read
Learn how nanopore sequencing improves the monitoring of infectious disease outbreaks.
Blue DNA chain surrounded by ones and zeroes and in the middle of a series of blue circles.
Hidden Messages in DNA Could Reduce Biosecurity Risks
Danielle Gerhard, PhD | Oct 15, 2024 | 7 min read
To improve traceability and enable authentication of synthetic nucleic acid sequences, researchers are embedding digital signatures into DNA.
A skull is seen on the forest floor; above it, magnified and in circles, are a blow fly, bacteria, and a carrion beetle.
Science Experiments from the Afterlife
Hannah Thomasy, PhD | Oct 15, 2024 | 2 min read
Forensic anthropologists, microbiologists, and entomologists study donated cadavers to determine how human bodies decompose.
Blue and pink DNA helix and human lungs on a blue background.
Nanoparticles Breathe New Life into Lungs
Sneha Khedkar | Oct 15, 2024 | 4 min read
Lipid nanoparticles deliver CRISPR tools directly to lung stem cells, offering new therapeutic avenues for treating genetic diseases.
The infographic shows a new method where researchers used spider webs to monitor environmental eDNA of vertebrates. They demonstrated the effectiveness of their by analyzing samples from a zoo and a wildlife sanctuary.
A Spider-Web Trap to Monitor Environmental DNA
Mariella Bodemeier Loayza Careaga, PhD | Oct 15, 2024 | 1 min read
Sticky spider-web traps are promising non-invasive and cheap tools for terrestrial vertebrate monitoring.
3D illustration of a yellow DNA polymerase binding to a blue strand of DNA.
DNA Polymerase Works in Short Bursts Rather than One Long Stretch
Shelby Bradford, PhD | Oct 14, 2024 | 4 min read
The enzyme that copies and repairs DNA is more dynamic than originally thought.
Vizgen, Inc
Vizgen and Ultivue Merge to Enable Deeper Insights into Disease Mechanisms and Drive Innovation in Spatial Multi-Omics
Vizgen Inc | Oct 9, 2024 | 2 min read
Combined single-cell spatial genomics and multiplex proteomic profiling technologies position merged company to accelerate discoveries in foundational and clinical research
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