electrophysiology

Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed.

Researchers use a high throughput microelectrode array platform to test neural activity in an in vitro model of ALS.

Tapeworm larvae may cause seizures by releasing excitatory amino acids into the brain.

Researchers discovered novel attractants that may improve Tsetse fly traps and help control disease spread.

The DishBrain system can send and receive electrophysiological signals to and from living neurons, training the cells to accomplish a task.

So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell’s activity.

Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.

Researchers have recorded tens of thousands of brain cells in mice as the animals transitioned from feeling thirsty to quenched.

Recordings of electrical activity in porcine brains finds similarities to rodent neural tissue.

After a decades-long pursuit, researchers have confirmed the identity of the pore of the mechanotransduction channel in vertebrates’ inner ear hair cells.

Software that can separate signals from noise brings neuroscientists a step closer to understanding neurons’ patterns of communication.

Micrometer-size magnetrodes detect activity-generated magnetic fields within living brains.

Newly designed sensors detect the magnetic fields generated by electrical activity within cat brains.

Deep within the forebrains of mice, scientists have identified an elusive cell type responsible for forming habits.

Two groups of scientists combined automation with two-photon microscopy to target and record specific neurons in living animals. 

Imaging and manipulating the brain has come a long way from electrodes and the patch clamp, though such traditional tools remain essential.

Flexible patches of silicone that stick to skin and conduct electricity could serve as the basis for a new, reusable electrode for medical applications.

The Scientist’s choice of major improvements in imaging, optogenetics, single-cell analyses, and CRISPR