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An illustration of a blue brain with the cerebellum highlighted in pink.
New Cilia Disassembly Pathway Revealed in Maturing Neurons
Volume electron microscopy reveals a novel cellular process that is critical for healthy brain development, with implications for tumor formation.
New Cilia Disassembly Pathway Revealed in Maturing Neurons
New Cilia Disassembly Pathway Revealed in Maturing Neurons

Volume electron microscopy reveals a novel cellular process that is critical for healthy brain development, with implications for tumor formation.

Volume electron microscopy reveals a novel cellular process that is critical for healthy brain development, with implications for tumor formation.

electron microscopy

Jotham Austin, the advanced electron microscopy core director at the University of Chicago, stands in the facility beside an EM instrument, helping a student who is sitting at the computer.
Career Chat: Choosing a Core Career Track
Shelby Bradford, PhD | Oct 17, 2024 | 5 min read
Jotham Austin opted for a director of a core facility position to combine his love for electron microscopy, teaching, and technique development.
JFT1 has reacted with hydrogen peroxide and APEX2 to create red fluorescence near APEX2 that remains separate from the green mitochondria.
FLEXing a Bright New Idea
Shelby Bradford, PhD | Sep 16, 2024 | 1 min read
A modified fluorescent protein scheme survives harsh electron microscopy conditions, offering new solutions for dual imaging.
A person’s hand reaching for wheat.
Close Encounters of Skin and Nerve Cells
Kamal Nahas, PhD | Apr 11, 2024 | 4 min read
Scientists exploring the skin-nerve cell connection have only scratched the surface. New research highlights just how intertwined the two cells are.
Charting a New Course Through the Injured Brain
Rashmi Shivni | Jan 15, 2024 | 4 min read
A state-of-the-art technique helps scientists map out tissue at the single cell level after a demyelinating brain injury.
Using Mass Photometry to Assess and Characterize Protein Samples 
Rapidly Characterizing Complex Samples With Mass Photometry
The Scientist | Jan 12, 2024 | 1 min read
In this webinar, Perla Vega and Philip Kitchen will explore how scientists can use mass photometry to assess sample quality and characterize proteins.
Infographic detailing two volume electron microscopy modalities.
Infographic: Drivers of the Expansion of Volume Electron Microscopy
Danielle Gerhard, PhD | Sep 8, 2023 | 2 min read
Technological advancements over the last two decades transformed volume electron microscopy, improving usability, resolution, and throughput.
This image depicts the fruit fly nerve cord connectome. It highlights 930 neurons, a subset of the full set of reconstructed neurons.
The Expansion of Volume Electron Microscopy
Danielle Gerhard, PhD | Sep 8, 2023 | 6 min read
A series of technological advancements for automation and parallel imaging made volume electron microscopy more user friendly while increasing throughput.
 Dive into Cryo-EM’s History, Milestones, and Insights.
Cryo-EM: Building on a History of Invention and Innovation
Thermo Fisher Scientific | Aug 2, 2023 | 1 min read
From humble yet ingenious beginnings to Nobel recognition, cryogenic electron microscopy (cryo-EM) provides insights into scientific questions that other technologies are unable to answer.
Neurons in all sorts of different colors, some glowing
How Fear Restructures the Mouse Brain
Natalia Mesa, PhD | Aug 15, 2022 | 4 min read
By combining deep learning and electron microscopy, researchers now have a more detailed understanding of how fear changes the brain.
Form Determines Function: Insights from Structural Biology
The Scientist | Jul 23, 2021 | 1 min read
Researchers use diverse tools to analyze protein structures.
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
An illustration of a flask of bacteria, a weighted microscope slide, and two bacteria exchanging materials via nanotubes.
Infographic: Sources of Variation in Bacterial Nanotube Studies
Sruthi S. Balakrishnan | Jun 1, 2021 | 2 min read
Differences in how researchers prepare and image samples can lead to discrepancies in their results.
Transforming Virology Research with Cryo-EM
The Scientist and Thermo Fisher Scientific | May 11, 2021 | 1 min read
Explore what researchers can do with Cryo-EM
Coronavirus Closeup, 1964
Ashley Yeager | Sep 1, 2020 | 3 min read
Electron microscopy revealed that a deadly disease of birds was not a form of flu, but a different type of virus entirely.
Coronavirus-Infected Cells Grow Filopodia
Shawna Williams | Jun 30, 2020 | 1 min read
SARS-CoV-2 causes cells to put out projections that spread the virus, a study finds.
Image of the Day: Coronavirus Under the Scope
Amy Schleunes | Feb 17, 2020 | 1 min read
The National Institute of Allergy and Infectious Diseases releases a series of images that offer a close up look at the novel coronavirus SARS-CoV-2.
Imaging Chromatin to Deduce Function from Form
Marissa Fessenden | Dec 1, 2018 | 7 min read
Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.
Aaron Klug, Developer of Crystallographic Electron Microscopy, Dies
Ashley P. Taylor | Nov 26, 2018 | 3 min read
The chemist and biophysicist won a Nobel prize for the development of a technique to probe the structures of nucleotide-protein complexes.
Image of the Day: Feather Mites
The Scientist and The Scientist Staff | Feb 19, 2018 | 1 min read
Researchers used scanning electron microscopy to peer at bugs on several hummingbird species.
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