ADVERTISEMENT
The illustration shows floating chromosomes with a Y-shaped chromosome in the foreground.
Closing the Gaps in the Human Genome: Why Y Was the Final Hurdle
For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.
Closing the Gaps in the Human Genome: Why Y Was the Final Hurdle
Closing the Gaps in the Human Genome: Why Y Was the Final Hurdle

For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.

For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.

DNA

The illustration shows floating chromosomes with a Y-shaped chromosome in the foreground.
Closing the Gaps in the Human Genome: Why Y Was the Final Hurdle
Kamal Nahas, PhD | Aug 28, 2023 | 4 min read
For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.
Equally-sized droplets of a nucleic acid sample.
Digital PCR: The Journey to Superior Data 
Bio-Rad Laboratories | Aug 24, 2023 | 1 min read
With digital PCR (dPCR), researchers accurately and precisely quantitate nucleic acid samples.
An older woman wearing a blue suit, shaking hands with an older man wearing a black suit.
Iconic Geneticist Evelyn Witkin Dies at Age 102
Lisa Winter | Jul 24, 2023 | 3 min read
Lasker Award winner Evelyn Witkin discovered the mechanism for DNA repair following UV damage.
Sir Richard Roberts won the 1993 Nobel Prize “for their discoveries of split genes.” 
How Restriction Enzymes Changed Biology
Nathan Ni, PhD | Jun 1, 2023 | 4 min read
Endonuclease R changed Richard Roberts’ career trajectory and created an industry.
Beams of colored fluorescent light Beams of colored fluorescent light
A Complete Guide to Absorbance and Fluorescence Quantification
DeNovix Inc. | May 9, 2023 | 1 min read
Learn when to select absorbance or fluorescence to assess sample quantity and quality.
Ribbon diagram of the bacterial histone Bd0055
Bacteria Have Histones After All: Study
Kamal Nahas, PhD | Feb 14, 2023 | 4 min read
Researchers identify hundreds of candidate histone proteins in bacteria, including one with an unusual way of binding to DNA.
Strategies to overcome common qPCR challenges
Real-Time PCR Tips and Tricks
Analytik Jena | Jan 19, 2023 | 1 min read
Strategies to overcome common qPCR challenges
An artist’s rendering of a DNA-based virus trap, represented as gray rods in a short cone-shaped arrangement. One is coated with blue molecules, likely antibodies, that adhere to a virus target. Another image shows to traps coming together to capture a red coronavirus.
“Origami” DNA Traps Could Keep Large Viruses From Infecting Cells
Natalia Mesa, PhD | Jan 18, 2023 | 4 min read
By engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.
Better Ways to Extract DNA
Better Ways to Extract DNA
The Scientist | Jan 17, 2023 | 1 min read
Learn how to obtain high throughput DNA purification that improves next-generation sequencing.
Artist’s rendering of a reflective metallic DNA double helix.
Humans Are Still Evolving Thanks to Microgenes
Natalia Mesa, PhD | Jan 4, 2023 | 3 min read
A study sheds light on the tiny genes that have evolved in human genomes since we split from our mammalian ancestors.
A collection of images from prior stories, including illustrations of DNA, chromosomes, and various cells, microscopy images of cancer cells, and a photo of a mouse on a treadmill.
Our Favorite Cancer Stories of 2022
Dan Robitzski | Dec 27, 2022 | 4 min read
This year, cancer researchers uncovered a variety of ways that tumors can survive and spread, ranging from damaging their own DNA to exploiting the nearby microenvironment for nutrients.
Genomic data. Dna test infographic, molecule structure genetic sequencing chart and chromosome architecture genealogy diagram, vector concept stock illustration
Unearthing Hidden Family Secrets: Tracing the Lineage of a Centuries-Old Grand-Mummy
Iris Kulbatski, PhD | Dec 13, 2022 | 3 min read
Researchers show how a toxic therapy helped identify a mummy using preserved DNA.
Analyze Single-Stranded Oligonucleotide Purity 
Analyzing Oligonucleotide Purity with Capillary Electrophoresis
Agilent | Nov 7, 2022 | 1 min read
Identify small impurities introduced by oligonucleotide synthesis prior to experimentation.
Technique Talk: Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
The Scientist | Oct 21, 2022 | 1 min read
In this webinar, Jia Guo discusses the basics of in situ hybridization and how to use novel fluorescent probes for ultra-sensitive single-cell resolution in situ genomics.
Exploring quality standards for extracting high yields of DNA from biological samples 
Best Practices for Preparing High-Quality DNA Samples
Bertin Instruments | Oct 18, 2022 | 1 min read
Exploring quality standards for extracting high yields of DNA from biological samples
blue-gloved hands pipetting from test tube
What’s Next for Ancient DNA Studies After the Nobel?
Mary Prendergast, The Conversation | Oct 5, 2022 | 4 min read
The award highlights tremendous opportunities for aDNA as well as challenges related to rapid growth, equity, and misinformation.
Fluorescent microscopy images of cells after being transfected.
Universal Transfection Reagents: Improving Efficiency and Decreasing Cell Toxicity
The Scientist, MilliporeSigma, and Roche | Oct 5, 2022 | 4 min read
Researchers optimize their transfection protocols with the ideal transfection reagent that has multiple applications, low cytotoxicity, and high transfection efficiency.
VAI
One Sequence, Many Variations
Van Andel Institute | Oct 5, 2022 | 5 min read
Andrew Pospisilik explores the epigenetic changes that give organisms the plasticity to change in response to their environments.
Microscopic view of monkey cells in orange and blue
Science Snapshot: More Fun Than a Barrel of Monkey Cells
Lisa Winter | Oct 3, 2022 | 1 min read
This year’s second-place winner of the 2022 Nikon Small World in Motion competition shows a 12-hour time-lapse of labeled cells.
White mice in a clear plastic cage
Different Genes Influence Lifespan in Male and Female Mice
Natalia Mesa, PhD | Sep 29, 2022 | 3 min read
Researchers say there may be similar, human genes whose effects on lifespan vary by sex.
ADVERTISEMENT