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An illustration of a purple and blueribosome using mRNA as a template to synthesize a red protein chain.
A Small RNA with a Big Impact on Cell Aging
Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight.
A Small RNA with a Big Impact on Cell Aging
A Small RNA with a Big Impact on Cell Aging

Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight.

Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight.

Biochemistry

Fluorescent light beams
Bringing Confocal Imaging to Life with Fluorescence Lifetime Information
Leica Microsystems | Sep 24, 2024 | 1 min read
A revolutionary set of imaging tools helps researchers maximize the insights obtained from every fluorescence experiment. 
Discover Why Ultrapure Water is Critical for HPLC and LC-MS
The Importance of Water Purity when Studying Endocrine Disruptors
ELGA Veolia | Sep 19, 2024 | 1 min read
Detecting endocrine disrupting compounds for monitoring or characterization requires ultrapure water for consistent results. 
Image of Lasker laureate Zhijian “James” Chen. He wears glasses and a light blue shirt under a dark blue sweater. He smiles at the camera.
DNA-Sensing Enzyme Wins the 2024 Lasker Award
Laura Tran, PhD | Sep 19, 2024 | 7 min read
Zhijian “James” Chen received this year’s Albert Lasker Award for discovering cGAS, an enzyme which scopes out DNA-based threats and alerts the immune system.
Vector illustration of researchers and doctors investigating gastrointestinal disorder detection and treatment.
Detecting Gastrointestinal Pathogens with Molecular Diagnostics 
The Scientist Creative Services Team in collaboration with Thermo Fisher Scientific | Sep 17, 2024 | 1 min read
Explore how PCR diagnostics support timely detection, targeted treatment, and surveillance of gastrointestinal pathogens.
Two male scientists working in a laboratory.
A Matter of Molecular Attraction
Mariella Bodemeier Loayza Careaga, PhD | Sep 16, 2024 | 2 min read
While studying the metabolism of the developing chick embryo, Marià Alemany Lamana’s team acted quickly to avert an error.
JFT1 has reacted with hydrogen peroxide and APEX2 to create red fluorescence near APEX2 that remains separate from the green mitochondria.
FLEXing a Bright New Idea
Shelby Bradford, PhD | Sep 16, 2024 | 1 min read
A modified fluorescent protein scheme survives harsh electron microscopy conditions, offering new solutions for dual imaging.
Researchers at the University of Arizona developed a pH-responsive probe that activated in the basic environment (purple) of the larval midgut and bound to gut proteins.
Gut-Powered Mosquito Probes
Laura Tran, PhD | Sep 16, 2024 | 2 min read
With the rise of insecticide resistance, researchers crafted a novel probe that selectively targets mosquito larvae’s weak spot.
Collection of green and blue proteins with different conformations on a black background.
The Dynamic Lives of Intrinsically Disordered Proteins
Danielle Gerhard, PhD | Sep 13, 2024 | 10+ min read
Shapeshifting proteins challenge a long-standing maxim in biology.
Infographic depicting the variety of conformations that proteins can assume and how this facilitates multifunctionality.
Infographic: Shapeshifters in the Proteome
Danielle Gerhard, PhD | Sep 13, 2024 | 2 min read
Textbooks often depict proteins as nicely folded three-dimensional structures, but many proteins are far from it.
Image of blue and red worms navigating across a maze from left to right. The far right depicts a finish line for the worms.
Drunk Worms Wiggle Their Way to an Ig Nobel Win
Laura Tran, PhD | Sep 12, 2024 | 4 min read
University of Amsterdam researchers claimed the 2024 Ig Nobel Prize in Chemistry for studying polymers by racing inebriated and sober worms through a chromatography maze.
Winning Westerns: Tips and Tricks for Protein Electrophoresis and Western Blotting
Winning Westerns: Tips and Tricks for Protein Electrophoresis and Western Blotting
The Scientist Staff | Sep 12, 2024 | 1 min read
In this webinar, Kelly Wolfe will highlight how to obtain more reliable and reproducible western blots.
Winning Westerns: Tips and Tricks for Protein Electrophoresis and Western Blotting
Winning Westerns: Tips and Tricks for Protein Electrophoresis and Western Blotting
The Scientist Staff | Sep 12, 2024 | 1 min read
In this webinar, Kelly Wolfe will highlight how to obtain more reliable and reproducible western blots.
Sino Biological Logo
Sino Biological and BioGeometry Deepen Strategic Cooperation to Empower Protein R&D with Generative AI
The Scientist Staff | Sep 11, 2024 | 2 min read
This collaboration brings together Sino Biological’s advanced protein expression and wet-lab capabilities with BioGeometry’s generative AI protein design and optimization platform.
Illustration of blue and purple mitochondria.
Multifaceted Mitochondria Maintain Mystique
Shelby Bradford, PhD | Sep 11, 2024 | 3 min read
Tiny but mighty, the mitochondria continue to surprise scientists with new insights into their diverse roles within cells.
Discover How Immunoassays Deliver Protein Biomarker Research Solutions
Protein Biomarker Research Solutions
The Scientist Creative Services Team in collaboration with MilliporeSigma | Sep 9, 2024 | 1 min read
Immunoassays help researchers across a range of applications from screening to targeted analysis.
Conceptual 3D illustration of cells secreting extracellular vesicles.
Extracellular Vesicles Go with the Flow
Beckman Coulter Life Sciences | Sep 4, 2024 | 1 min read
Explore a comprehensive guide to flow cytometry for extracellular vesicle analysis.
A syringe inserted into a vial of vaccine.
Engineered Yeast Brew a Vaccine Adjuvant 
Sahana Sitaraman, PhD | Sep 3, 2024 | 3 min read
Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.
A gel with dye-labeled bands indicating proteins separated by electrophoresis.
SDS-PAGE Technology for the 21st Century
The Scientist Staff | Sep 2, 2024 | 2 min read
New innovations streamline and simplify SDS-PAGE from a multi-hour workflow to a matter of minutes.
The hand of a scientist picking up a sample vial for LC-MS analysis
Prepare for LC-MS Analysis with Automation
Revvity | Aug 28, 2024 | 1 min read
Tissue dissociation and homogenization are excellent candidates for automation in LC-MS workflows, helping scientists achieve consistent and reproducible protein analysis.
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