Epigenetic Clocks Continue to Tick Over Multiple Lifetimes
Epigenetic Clocks Continue to Tick Over Multiple Lifetimes
Murine T cells that survived at least four host lifetimes offer insights into immunological senescence.
Murine T cells that survived at least four host lifetimes offer insights into immunological senescence.
acute lymphoblastic leukemia
Cancer Researcher Donald Pinkel Dies at Age 95
Natalia Mesa, PhD | Mar 18, 2022 | 3 min read
Unsatisfied by how treatments for childhood leukemia failed to prevent the disease’s return, Pinkel combined them all—and virtually cured the disease.
Genetic Screens Provide Clues About Prognosis, Risk of Second Cancer
Shawna Williams | Apr 1, 2018 | 5 min read
Mutations in the TP53 gene appear to influence the prognosis and likelihood of future cancers in pediatric leukemia patients.
First CAR T-Cell Therapy Approved in U.S.
Shawna Williams | Aug 30, 2017 | 1 min read
The genetically modified blood cells will be used for patients with a type of acute lymphoblastic leukemia, when other treatments fail.
FDA Votes Yes on CAR T-Cell Therapy
Aggie Mika | Jul 13, 2017 | 2 min read
A Food and Drug Administration advisory panel unanimously calls for agency approval of the cell therapy for the treatment of resistant leukemia.
Gene Editing Treats Leukemia
Karen Zusi | Nov 6, 2015 | 2 min read
One-year-old Layla Richards has remained cancer-free months after receiving an experimental gene editing therapy.
Tumor-Targeting T Cells Engineered
Chris Palmer | Aug 11, 2013 | 3 min read
Scientists genetically modify T cells derived from pluripotent stem cells to attack lymphatic tumors.
Immune System Versus Cancer
Dan Cossins | Apr 10, 2013 | 2 min read
Engineering the immune system to overcome tumor evasion strategies was a hot topic at this week’s AACR meeting, with researchers discussing several new approaches.
Leukemia Linked to Changes in Womb
Edyta Zielinska | Apr 10, 2013 | 1 min read
Genetic changes that may initiate childhood leukemia could originate while the baby is still in utero.
Contributors
Kate Yandell | Apr 1, 2013 | 3 min read
Meet some of the people featured in the April 2013 issue of The Scientist.
Up, Up, and Array
Megan Scudellari | Apr 1, 2013 | 8 min read
By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.